Hype and misinformation about GcMAF. Ineffective and potentially toxic products. Pure, real GcMAF vs. phonies. Types of GcMAF knockoffs. About purity. GcMAF production. Contamination. Certification. Caveat emptor!!
The emergence of GcMAF therapy and Nagalase testing as viable methods for treating and preventing cancer will inevitably be accompanied by genuine concern and debate about how best to put these valuable tools to work. Paralleling these positive efforts to prevent suffering and save lives, negative forces will exude from the swamp of diabolical human greed. Slick hucksters will offer stuff called “GcMAF” that doesn’t work—and may even be harmful. Ineffective imitations and counterfeit products will appear, including knockoffs, copycats, phonies, bootlegs, and wannabes. There will be nay-sayers and disinformation campaigns trying to convince you this is all a big hoax. And, as we all know, the internet is rife with hype and misinformation; GcMAF/Nagalase will be no exception.
What’s a person desperately in need of cancer or HIV treatment to do? The urge to buy into false hope may be difficult or impossible to overcome.
Pure, real GcMAF vs. the phonies
Because it is identical to that which the body makes (i.e., bioidentical), pure GcMAF will never cause symptoms of any kind. When symptoms appear in an individual taking GcMAF, the cause is impurity, contamination, or both.
The phonies will come in packages that look exactly like quality-certified products. Packaging replication technology has advanced to the point where even brand-name manufacturers can’t tell the difference between their own products and the knockoffs without chemically testing the ingredients. People will die needlessly because they put their faith in phony GcMAF products.
Types of GcMAF knockoffs
A huge market for GcMAF will emerge as it becomes a household word. The already substantial risk of impure, contaminated, and inactive products will then skyrocket. Hucksters will ooze from the woodwork, hawking “GcMAF” that will range from inactive and harmless to toxic and dangerous. There will be different types of knockoffs:
Bootleg or wannabe versions: serious attempts to make GcMAF that have fallen short and are impure, contaminated, and/or potentially toxic. Bootleg versions can be pure but “dirty,” containing contaminants that cause muscle aches, flu-like symptoms or fatigue. A bootleg could also be pure (in the sense of clean), but non-bioidentical, and therefore too weak in its macrophage activating power to be effective.
Phony versions: packaged to look exactly like the real thing, but totally inactive. The “GcMAF” might be powdered sugar, starch, or any (hopefully) harmless white powder that, like GcMAF, disappears when put into solution with water. The phony product might simply contain nothing at all: several hundred nanograms of GcMAF in a vial, sans water, would be about the size of a small speck of dust.
As mentioned above, nowadays it is possible to so exactly copy a bottling and packaging process that even the authentic manufacturing company can’t tell, by examining the packaging alone, whether or not the product inside is real. Chromatography testing is required to make that determination.
I’ll never forget an experience I had several years ago. A patient told me she had been injecting human growth hormone (hGH) that she had been obtaining from a source in in Tijuana, via San Diego. She showed me the package and it looked real enough, as if it had come directly from the manufacturer: perfect box, red plastic-capped vial inside, flawless label, nothing suspicious. I suggested we test her blood for hGH, and when we did, there was none there! She had been injecting very expensive water! Obviously this was a perfect knockoff, and when I contacted the manufacturer (of the real product—a major brand name household word drug company), they told me that even they were unable to tell by the packaging alone whether or not a given product was the real thing. They had to test the ingredients to be sure it was theirs! Perfect packaging tells you nothing.
Purity and GcMAF production
A “pure” protein contains only molecules of a single protein, and no other molecules of any kind. Impurities cause compromised effectiveness, adverse reactions, and symptoms of toxicity. Making “pure” GcMAF is not a simple undertaking. So far, the only human being to have succeeded in making pure GcMAF is Professor Nobuto Yamamoto. The process is not that complicated, however. Dr. Yamamoto provides specific instructions in his research papers. A good biochemist with proper equipment could easily make GcMAF. The raw materials are inexpensive and a large scale manufacturing operation should make for a price tag that’s within reach of the average person.
GcMAF can be made via recombinant DNA technology by inserting a small section of DNA into the bacterium E. coli. This piece of DNA reprograms the bacterium to make GcMAF. An impurity can be introduced at any step in this multistage protein manufacturing process.
For example, once these reprogrammed bacteria are incubated and have generated the GcMAF from their revised genetic program, the newly made GcMAF must be separated from the E. coli and then purified. If some of the E. coli (or any of the many other chemicals generated by E. coli) are left behind with the GcMAF, you have a troublesome impurity. Endotoxins are an especially common E. coli byproduct impurity; these typically cause flu-like symptoms. Solvents and surfactants can likewise be left behind in the purification process.
Impurities don’t necessarily affect the macrophage activating power of the GcMAF product, but they can and do cause side effects such as fatigue, weakness, malaise, and muscle and joint pain. These symptoms can be so uncomfortable for the patient that it becomes impossible to tolerate the beneficial effects they would otherwise obtain from the GcMAF.
Contamination occurs when a foreign agent gets into the GcMAF product from the outside (rather than being introduced as a part of the manufacturing process). Contaminants can cause symptoms similar to those due to impurities (fatigue, weakness, malaise, and muscle and joint pain). Contaminants can be airborne, or carried into the (otherwise sterile) production lab environment by hapless humans—on their hands, feet, or clothing. They can enter via the lab’s water and air supply. A cough from a person with a bacterial respiratory infection could cause big problems. Contamination via molds, viruses, and bacterial species is very common in biotech production facilities and requires hygiene precautions so elaborate they make surgical scrubbing look like a cakewalk. Entering a biotech production facility is like dressing for a walk in outer space: cap, gloves, full body gown, mask, booties. You don’t need oxygen tanks, but the air you breathe must be filtered to remove dust, toxic chemicals, and pathogenic microorganisms.
Potency (quantified as macrophage activation)
Assuming we have a pure GcMAF product, then what about activity or potency? In the world of macrophages, potency is activity. The degree to which GcMAF activates macrophages is our measure of potency. Only pure, bioidentical GcMAF will provide the level of optimum macrophage activation necessary to reverse cancers and viral infections.
Extremely sensitive receptors on the surface of macrophages are happiest when they are stimulated by pure GcMAF. Rearrange even a few atoms, much less a few amino acids, and the “GcMAF” will not look the same to those receptors and either they won’t recognize it at all, or their response will be halfhearted. So, beyond purity, the GcMAF product must also be tested for macrophage activating power. This test literally asks the macrophages, “Do you recognize this particular batch of GcMAF?” And, “How much does it activate you?” Because this involves working with live human macrophages, it is not easy. To determine the macrophage activating power of pure bioidentical GcMAF, Professor Yamamoto quantified rate of phagocytosis of cancer cells (a 30 fold increase), rate of generation of superoxide radicals (15 fold), and rate of macrophage proliferation (40 fold).
It will be necessary to establish a consumer protection certification program whereby product offerings—when they do become available—will be subjected to rigorous testing and then certified for both purity and activity.
Caveat emptor!!* Buyer beware!!
In the meantime, if you are offered a “GcMAF” product, be aware that at this point in time there is no product that has been independently tested and verified as pure, contaminant-free, toxin-free, bioactive GcMAF. We are hoping this situation will change, and when it does, my website, www.gcmafnow.org, will report it.